ea0034p50 | Clinical biochemistry | SFEBES2014
Shotton Rohan
, Perogamvros Ilias
, Keevil Brian
, Monaghan Philip
, Trainer Peter
, Higham Claire
Background: The use of salivary cortisol is well validated in the diagnosis of Cushings syndrome but routine use of salivary measurements during dynamic tests of HPA axis sufficiency is uncommon and reference ranges are not established. Salivary cortisol (SalF) and cortisone (SalE) measurements by LCMS have several advantages including ease of collection and more accurate reflection of unbound serum cortisol levels in conditions of altered CBG levels (e.g. oestroge...